Making Discoveries that Make a Difference

Animal Models of Viral Infections

The following animal models of viral infections have either been established or are under development at the BRL.  These models are available for therapeutic and vaccine testing.  For more information, please contact Dr. Kylene Kehn-Hall.

To see the animal model, please click on the animal model description.

Models Currently Available

Family GenusSpeciesStrainRoute of InfectionAnimal Model
TogaviridaeAlphavirusVenezuelan Equine Encephalitis VirusTC-83IntranasalC3H/HeN Mice (BSL-2)
TogaviridaeAlphavirusVenezuelan Equine Encephalitis VirusTrDIntranasal and aerosolBALB/c Mice
BunyaviridaePhlebovirusRift Valley fever virusMP12IntraperitonealIFNAR-/- Mice (BSL-2)
BunyaviridaePhlebovirusRift Valley fever virusMP12-LucIntraperitonealIFNAR-/- Mice (BSL-2)
BunyaviridaePhlebovirusRift Valley fever virusZH501SubcuteneousBALB/c Mice (BSL-3)

Models Under Development

Family GenusSpeciesStrainRoute of InfectionAnimal Model
TogaviridaeAlphavirusEastern Equine Encephalitis VirusGA97Intranasal and aerosolCD-1 Mice (BSL-3)
TogaviridaeAlphavirusWestern Equine Encephalitis VirusCalifornia 1930Intranasal and aerosolCD-1 Mice (BSL-3)
TogaviridaeAlphavirusWestern Equine Encephalitis VirusMcM.FLUCIntranasal and aerosolCD-1 Mice (BSL-3)
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